Ayda Yari Ilkhchi
Azarbaijan Shahid Madani University, Iran
Title: Effects of modified Graphene oxide on nervous tissue regeneration
Biography
Biography: Ayda Yari Ilkhchi
Abstract
Nervous system lesions are generally entangling and crucial problems worldwide. Renovation and recovery of nervous system damages, because of their function and anatomy, have been challenging compared with other tissues. The spinal cord injury (SCI) is a portion of central nervous system (CNS); almost two million people suffer from it throughout the world. Recently treatment and regeneration of damaged tissue, sensory recovery and motor function are investigated by different researchers globally. Graphene oxide (GO)-based nanomaterials as considerable materials, with wonderful and precious properties, propose numerous chances for designing pioneer scaffolds in neural tissue engineering to cure the central and peripheral nervous system injuries by neuroregenerative therapies. In this study, GO was synthesized by Modified Hummer method. In order to improve functionality and biocompatibility of GO, was modified with polymers. Follow up chemical analysis; we are investigating in vitro (cell culture) and in vivo (mice model).
The results of analysis show a successful structural and morphological preparation. It is anticipated that Graphene nanomaterials indicate a strong performance in proliferation and differentiation of neural cells, recovery and regeneration of damaged neurites, due to the significant flexibility, extraordinary electrical, mechanical, morphological, and chemical properties.